Age leading to gut dysbiosis

Recently I came across a fascinating article in journal of microbiome which illustrates link between gut microbiota and inflammation. As we know from past research that chronic inflammation in our body leads to aging and disease processes.

 Several studies have indicated that older adults have an altered composition of the gut microbiota. With advancing age we tend to lose healthy gut bacteria. This altered composition is termed “Dysbiosis”. Evidence indicates that dysbiosis is associated with the presence of several key circulating inflammatory analytes like IL-6 and IL-8. The increase in proinflammatory cytokine leads to immuno-senescence or decrease immune system.

There are many health conditions that have shown to arise from possibly altered microbiome which includes cystic fibrosis , inflammatory bowel conditions (irritable bowel syndrome, Crohn’s disease, and colon cancer , neurological diseases (Parkinson’s disease, Alzheimer’s disease, and multiple sclerosis), metabolic diseases (obesity and diabetes) , as well as musculoskeletal conditions (frailty, osteoporosis, rheumatoid arthritis, and gout).

Hence, based on somewhat limited knowledge that we have for gut microbiota it is proposed that dietary supplementation with probiotics appears to be among the most promising interventions for re-balancing the gut microbiome. Well-known actions of probiotics include antimicrobial activity, enhancement of intestinal barrier function, and immunomodulation via actions on a wide variety of immune cells.

Other factors that can contribute to replenish gut microbiota include caloric restriction and/or implementing a Mediterranean-style diet, and physical exercise.

Simply Biotic are the best probiotics which provides 10 strains of bacteria (acidophilus, lactobacillus and bifidobcaterium) and a high bacterial count (25-50 billion CFUs) to replenish the gut microbiome. Take one capsule in the morning with any fruit which is a natural source of prebiotic and helps in growth of bacteria.  Probiotics aids in providing complete digestive health and boosts immunity. Simply biotic is reasonable and the best probiotic available in the market.

I believe, 21st Century will be dedicated to the understanding of gut microbiome and its preservation to prevent illnesses and for better health.